| Characteristic | Details |
|---|---|
| Active Ingredient | Sildenafil Citrate |
| Available Dosages | 50 mg, 100 mg |
| Administration Route | Oral |
| Indication | Erectile Dysfunction |
| Time to Onset | 30-60 minutes |
| Duration of Action | 4-6 hours |
| Learn More About Caverta | |
Pharmacokinetics
The pharmacokinetics of Caverta 100 mg define its absorption, distribution, metabolism, and excretion. Upon oral administration, sildenafil is absorbed rapidly. The plasma concentrations peak within 30 to 120 minutes. The bioavailability stands at about 40%, though it can vary. Food intake, especially high-fat meals, can slow absorption.
Sildenafil exhibits a volume of distribution of approximately 105 liters, indicating distribution in the body’s tissues. It is highly protein-bound, specifically to plasma proteins, up to 96%. Metabolism occurs predominantly in the liver through CYP3A4 and CYP2C9 isoenzymes. The major circulating metabolite is also active.
Excretion involves fecal and renal pathways. The terminal half-life is about four hours, facilitating a duration of action up to six hours. Renal impairment impacts clearance, necessitating dosage adjustments. Consider these pharmacokinetics when tailoring Caverta prescriptions for optimal efficacy.
Mechanism of Action
Sildenafil 100 mg operates by inhibiting phosphodiesterase type 5 (PDE5). This enzyme degrades cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. By blocking PDE5, sildenafil promotes cGMP accumulation.
The enhanced cGMP levels cause smooth muscle relaxation in the penile arteries. This process augments blood flow, resulting in an erection. Note that sexual stimulation is a prerequisite. Without it, sildenafil will not induce an erection.
While PDE5 inhibition is its primary action, sildenafil exhibits minor effects on other PDE isoenzymes. This specificity reduces the likelihood of off-target effects. Its ability to selectively target PDE5 underpins its role in erectile dysfunction therapy.
Caverta Precautions
Safety is paramount when using Caverta. Individuals must assess for contraindications such as severe cardiovascular disorders, recent myocardial infarction, or stroke. Hypotensive patients should exercise caution.
Concomitant use with nitrates or nitric oxide donors is contraindicated. The risk of significant hypotension exists. Patients with retinitis pigmentosa should avoid sildenafil due to potential vision complications.
Consider potential drug interactions. Concomitant CYP3A4 inhibitors or inducers can alter sildenafil levels. Antihypertensives may exacerbate hypotensive effects. Alcohol consumption can intensify side effects.
These precautions ensure a safe therapeutic experience. They minimize risks associated with sildenafil use. Practitioners must evaluate patient history diligently.
Caverta Storage
Proper storage of Caverta maintains its integrity and effectiveness. Store it at room temperature. Keep it away from excess heat and moisture.
Avoid storing in bathrooms or damp areas. The humidity can degrade the tablet. Keep Caverta in its original packaging until ready for use.
Ensure that medications remain out of children’s reach. They should remain securely sealed. Inspect expiry dates regularly to ensure viability.
Caverta Signs and Symptoms of Overdose
An overdose of sildenafil 100 mg can manifest in several ways. Symptoms may include severe dizziness, fainting, or prolonged erection. Gastrointestinal disturbances like nausea and diarrhea might occur.
Individuals may experience vision changes or blurred vision. Tachycardia and chest pain are possible. Immediate medical attention is crucial in overdose situations.
Accurate dosage adherence minimizes overdose risk. Patients should never exceed prescribed amounts. Any concerns should prompt physician consultation.
Caverta for Sale Online
Online marketplaces offer a convenient avenue to purchase Caverta. Numerous verified platforms ensure safe transactions. Accessing Caverta online grants privacy and discretion.
Authenticity is a priority. Ensure purchase from licensed pharmacies. Verify certification and compliance with regulatory standards.
Be wary of counterfeit products. Examine seller reviews and product ratings. A reliable vendor provides assurance of genuine Caverta.
- Convenience
- Privacy
- Authenticity
Exploring online options expands availability. This flexibility aids those seeking discreet solutions. Caverta remains accessible through trusted online channels.
